THE EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF SAFFRON STIGMA (CROCUS SATIVUS L.) ON METABOLIC CONTROL PARAMETERS, LIVER ENZYMES, AND RENAL FUNCTION PARAMETERS IN TYPE 2 DIABETIC PATIENTS

11/14/2021

THE EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF SAFFRON STIGMA (CROCUS SATIVUS L.) ON METABOLIC CONTROL PARAMETERS, LIVER ENZYMES, AND RENAL FUNCTION PARAMETERS IN TYPE 2 DIABETIC PATIENTS

Background: Uncontrolled metabolic status of diabetes induces multiple complications, such as liver and renal dysfunctions. Saffron as an herbal medicine may improve diabetes metabolic control.
Objective: The aim of this study was to investigate the effect of hydro-alcoholic extract of saffron on metabolic control parameters, liver enzymes, and renal function parameters in type 2 diabetic patients.
Methods: In this triple-blind clinical trial, 54 type 2 diabetic patients randomly consumed 15 mg saffron or placebo capsules twice a day for 8 weeks. The following measurements were made during the study: 1. Fasting and 2-hour blood glucose, glycosylated hemoglobin, cholesterol, triglyceride, low and high density lipoproteins, alkaline phosphatase, aspartate and alanine amino transferase, uric acid, blood urea nitrogen, and creatinine; 2. Physical activity at the beginning and the end of the study; 3. dietary intakes at the beginning, midst, and end of the study; 4. anthropometric parameters every 2 weeks; 5. blood pressure every 2 weeks. The data were analyzed using the SPSS.18 software.
Results: Fasting and 2-hour blood glucose, triglyceride, uric acid, and blood urea nitrogen decreased (35.5, 38.5, 0.62, and 4.5 mg/dl, respectively), and high density lipoprotein increased, significantly in the saffron group (P<0.05). Changes in lipid profile components other than triglycerides were not statistically significant in the two groups. Significant changes in blood pressure, dietary intakes, and physical activity were not seen in either group either (P>0.05).
Conclusion: Saffron hydro-alcoholic extract may improve type 2 diabetic patients’ condition through helping control blood glucose and some of the lipid profiles components. It can also improve renal function, which may be related to its antioxidant properties.

 

Other article

Sholezard
Sholezard
Sholezard with the taste of Ravang saffron

10/2/2019

Interactive effect of saffron supplement and resistance training on serum levels of sex hormones in young men
Interactive effect of saffron supplement and resistance training on serum levels of sex hormones in young men
Accordingly, it can be concluded that saffron supplementation and resistance training increase the reproductive function...

12/31/2019

Effect of planting density on flower and corm yield of Spanish and Iranian Saffron (Crocus sativus L.)
Effect of planting density on flower and corm yield of Spanish and Iranian Saffron (Crocus sativus L.)
With regard to the corm type, flower production was significantly higher in Iranian corms, while Spanish corms reinforce...

12/15/2019

Halva
Halva
Halva with saffron

9/7/2019

Anti-cancer properties of saffron
Anti-cancer properties of saffron
As a result, recent studies highly suggest that saffron stigma and its secondary metabolites can be considered as safe ...

8/27/2019

Drying effects on chemical and sensorial characteristics of saffron
Drying effects on chemical and sensorial characteristics of saffron
Drying in the shade could significantly reduce saffron pigments that should be avoided. As a result, roasting and electr...

12/30/2019

Pana cotta
Pana cotta
Pana cotta with the taste of Saffron

9/2/2019

Effect of saffron on patients with mild to moderate depression
Effect of saffron on patients with mild to moderate depression
results suggested that saffron can be as effective as a chemical medication Moreover, the regular use of saffron can lea...

8/22/2019

  • Customer Support
    Customer Support

    Ravang’s customer service phone number is +985133380000 and you can call that number 24 hours a day, seven days a week.

  • Free Shipping
    Free Shipping

    Free Shipping by Ravang is available for the purchases above 1500000 Rials.

  • Payment
    Payment

    Payment can be made through Saman payment gateway with Shetab cards.

  • Guaranteed Delivery
    Guaranteed Delivery

    Ravang Guaranteed Delivery guarantees the delivery dates and quality of products.