Effect of saffron on patients with mild to moderate depression

8/22/2019

Effect of saffron on patients with mild to moderate depression

Depression is a growing mental disorder among people. According to the World Health Organization, 350 million people (making up 5% of the world’s population) are suffering from depression. Fortunately, this disease can be treated even in its most severe form. As mentioned in Hamshari Online News, the Health Minister of Iran reported that more than 12% of Iranians are depressed.
Recently, numerous studies have been conducted to investigate the effect of saffron (i.e. a traditional Iranian spice) on the treatment of depression. One of these articles aimed to compare the effect of different doses of saffron on patients with mild to moderate depression. In the mentioned study, the antidepressant clinical effects of 40 and 80 mg of hydro-alcoholic extract of saffron were studied on 60 patients with mild to moderate depression for 6 weeks. The findings demonstrated that 80 mg of saffron can be beneficial for such patients and no side effect was observed.
The clinical experience of many psychiatrists indicated that patients do not cooperate appropriately for medication due to the side effects related to the administered drugs or fear of using chemical drugs. However, studies have shown that herbal medicine can be as effective as current treatments for depression in patients with mild to moderate depression. Saffron is considered as herbal medicine, which can positively improve the therapeutic procedure of depression.
Several clinical trials have compared the effects of saffron with fluoxetine and imipramine. The obtained results suggested that saffron can be as effective as a chemical medication Moreover, the regular use of saffron can lead to significant results, compared to placebo.


References
. (2014). The effects of 40 and 80 mg hydro- alcoholic extract of Crocus sativus in the treatment of mild to moderate depression, Journal of Mazandaran university of Medical Sciences,24, 48-53. 

 

 

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